product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLC38A9 Antibody
catalog :
MBS7044112
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot. Positive WB detected in:Jurkat whole cell lysate. All lanes: SLC38A9 antibody at 3.5ug/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 64,53,57 kDa. Observed band size: 64 kDa.
image 2 :
Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044112 at dilution of 1:100
image 3 :
Immunohistochemistry of paraffin-embedded human liver cancer using MBS7044112 at dilution of 1:100
product information
catalog number :
MBS7044112
products type :
Antibody
products full name :
SLC38A9 Antibody
products short name :
[SLC38A9]
products name syn :
[Sodium-coupled neutral amino acid transporter 9 Curated; Solute carrier family 38 member 9; SLC38A9]
other names :
[sodium-coupled neutral amino acid transporter 9 isoform 2; Sodium-coupled neutral amino acid transporter 9; sodium-coupled neutral amino acid transporter 9; solute carrier family 38 member 9; Solute carrier family 38 member 9]
products gene name :
[SLC38A9]
other gene names :
[SLC38A9; SLC38A9; URLC11]
uniprot entry name :
S38A9_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
498
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunofluorescence (IF)
image4 description :
Immunofluorescent analysis of U251 cells using MBS7044112 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
other info1 :
Species: Human. Immunogen: Recombinant human Sodium-coupled neutral amino acid transporter 9 protein
other info2 :
Conjugate: Non-conjugated. Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
products description :
Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
ncbi gi num :
385137120
ncbi acc num :
NP_001245215.1
ncbi gb acc num :
NM_001258286.1
uniprot acc num :
Q8NBW4
ncbi mol weight :
56,695 Da
uniprot summary :
SLC38A9: Putative sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Transporter, SLC family; Transporter; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: endoplasmic reticulum; late endosome; lysosome. Molecular Function: amino acid transmembrane transporter activity; protein binding. Biological Process: positive regulation of TOR signaling pathway
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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