product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Osteocalcin/Bone gla protein, OT/BGP ELISA Kit
catalog :
MBS704387
quantity :
48-Strip-Wells
price :
565 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS704387
products type :
ELISA Kit
products full name :
Human Osteocalcin/Bone gla protein, OT/BGP ELISA Kit
products short name :
bone gamma-carboxyglutamate (gla) protein
products name syn :
Human Osteocalcin/Bone gla protein; OT/BGP ELISA kit; RP11-54H19.5; BGP; OC; PMF1; bone Gla protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin) ; gamma-carboxyglutamic acid-containing protein; osteocalcin; bone gamma-carboxyglutamate (gla) protein
other names :
osteocalcin preproprotein; Osteocalcin; osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
products gene name :
BGLAP
other gene names :
BGLAP; BGLAP; OC; BGP; OCN; BGP
uniprot entry name :
OSTCN_HUMAN
reactivity :
Human
sequence length :
100
specificity :
This assay has high sensitivity and excellent specificity for detection of Human BGLAP. No significant cross-reactivity or interference between Human BGLAP and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml -20 ng/ml. Sensitivity: 0.078 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Biosynthesis/Metabolism. Protein Biological Process 3: Biomineralization
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for OT/BGP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any OT/BGP present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for OT/BGP is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of OT/BGP bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
40316933
ncbi acc num :
NP_954642.1
ncbi gb acc num :
NM_199173.4
uniprot acc num :
P02818
ncbi mol weight :
10,963 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); FGF Signaling Pathway (137989); Glucocorticoid Receptor Regulatory Network Pathway (138014); Interleukin-11 Signaling Pathway (698753); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prometaphase Pathway (105815); Notch-mediated HES/HEY Network Pathway (169347)
ncbi summary :
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
uniprot summary :
Function: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
size1 :
48-Strip-Wells
price1 :
565 USD
size2 :
96-Strip-Wells
price2 :
810
size3 :
5x96-Strip-Wells
price3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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