product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Angiopoietin 2, ANG-2 ELISA Kit
catalog :
MBS704338
quantity :
48-Strip-Wells
price :
465 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS704338
products type :
ELISA Kit
products full name :
Rat Angiopoietin 2, ANG-2 ELISA Kit
products short name :
angiopoietin 2
products name syn :
Rat Angiopoietin 2; ANG-2 ELISA Kit; AGPT2; ANG2; Tie2-ligand; angiopoietin-2; angiopoietin-2B; angiopoietin-2a; angiopoietin 2
other names :
angiopoietin-2; Angiopoietin-2; angiopoietin-2; angiopoietin 2
products gene name :
ANGPT2
other gene names :
Angpt2; Angpt2; Agpt2; Ang-2; Agpt2; ANG-2
uniprot entry name :
ANGP2_RAT
reactivity :
Rat
sequence length :
496
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat ANGPT2. No significant cross-reactivity or interference between Rat ANGPT2 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 47 pg/ml-3000 pg/ml. Sensitivity: 11.75 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Angiogenesis. Protein Biological Process 3: Angiogenesis
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ANG-2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ANG-2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ANG-2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ANG-2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
198278529
ncbi acc num :
NP_604449.1
ncbi gb acc num :
NM_134454.1
uniprot acc num :
O35462
ncbi mol weight :
56,518 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (1010919); HIF-1 Signaling Pathway (695233); Hemostasis Pathway (1010891); PI3K-Akt Signaling Pathway (692247); PI3K-Akt Signaling Pathway (692979); Rap1 Signaling Pathway (869320); Rap1 Signaling Pathway (878042); Ras Signaling Pathway (869318); Tie2 Signaling Pathway (1010920)
uniprot summary :
Function: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal
size1 :
48-Strip-Wells
price1 :
465 USD
size2 :
96-Strip-Wells
price2 :
655
size3 :
5x96-Strip-Wells
price3 :
2455
size4 :
10x96-Strip-Wells
price4 :
4595
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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