ELISA/assay

Rat Bone morphogenetic protein receptor 1A, BMPR-1A ELISA Kit

MBS704228

48-Strip-Wells

605 USD

ELISA Kit

Rat Bone morphogenetic protein receptor 1A, BMPR-1A ELISA Kit

bone morphogenetic protein receptor, type IA

Rat Bone morphogenetic protein receptor 1A; BMPR-1A ELISA Kit; 10q23del; ACVRLK3; ALK3; CD292; SKR5; OTTHUMP00000020014; activin A receptor; type II-like kinase 3; serine/threonine-protein kinase receptor R5; bone morphogenetic protein receptor; type IA

bone morphogenetic protein receptor type-1A; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor type-1A; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; bone morphogenetic protein 4 receptor; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor, type IA; Activin receptor-like kinase 3; ALK-3; Bone morphogenetic protein 4 receptor; CD_antigen: CD292

BMPR1A

Bmpr1a; Bmpr1a; BMP type-1A receptor; BMPR-1A; ALK-3

BMR1A_RAT

Rat

532

This assay has high sensitivity and excellent specificity for detection of Rat BMPR1A. No significant cross-reactivity or interference between Rat BMPR1A and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml-20 ng/ml. Sensitivity: 0.078 ng/ml

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

For example For the quantitative determination of rat bone morphogenetic protein receptor 1A (BMPR-1A) concentrations in serum, plasma, tissue homogenates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for BMPR-1A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any BMPR-1A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BMPR-1A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BMPR-1A bound in the initial step. The color development is stopped and the intensity of the color is measured.

13540661

NP_110476.1

NM_030849.1

Q78EA7

59,994 Da

Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460); Endochondral Ossification Pathway (219771); Hippo Signaling Pathway (749790); Hippo Signaling Pathway (750388); Signal Transduction Pathway (1010015); Signaling By BMP Pathway (1010142); TGF-beta Signaling Pathway (83456); TGF-beta Signaling Pathway (475)

may act as a serine/threonine kinase receptor; may mediate bone morphogenetic protein-induced bone formation [RGD, Feb 2006]

Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4 . Catalytic activity: ATP + [receptor-protein] = ADP + [receptor-protein] phosphate. Cofactor: Magnesium or manganese

48-Strip-Wells

605 USD

96-Strip-Wells

870

5x96-Strip-Wells

2950

10x96-Strip-Wells

5535