catalog number :
MBS7042028
products type :
Antibody Pair
products full name :
NEU3 Antibody Pair
products short name :
[NEU3]
products name syn :
[Sialidase-3; Ganglioside sialidase; Membrane sialidase; N-acetyl-alpha-neuraminidase 3; NEU3]
other names :
[NEU3 protein; Sialidase-3; sialidase-3; neuraminidase 3 (membrane sialidase); Ganglioside sialidase; Membrane sialidase; N-acetyl-alpha-neuraminidase 3]
products gene name :
[NEU3]
other gene names :
[NEU3; NEU3; SIAL3]
uniprot entry name :
NEUR3_HUMAN
concentration :
The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels.
storage stability :
Storage: -20°C
tested application :
Sandwich ELISA (EIA)
app notes :
We recommend using the capture antibody at a concentration of 0.1ug/ml and the detection antibody at a concentration of 0.125ug/ml. Optimal dilutions should be determined experimentally by the researcher.
other info1 :
Immunogen Species: Human. Components: Capture: MBS7042028 C. Detection: MBS7042028 D
other info2 :
Storage Buffer: Capture: 50% Glycerol, 0.01M PBS, PH 7.4. Detection: 50% Glycerol, 0.01M PBS, PH 7.4
ncbi acc num :
AAI36398.1
ncbi pathways :
Asparagine N-linked Glycosylation Pathway (1268714); Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway (1268715); Glycosphingolipid Metabolism Pathway (1270099); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Metabolism Of Proteins Pathway (1268677); Other Glycan Degradation Pathway (82976); Other Glycan Degradation Pathway (346); Post-translational Protein Modification Pathway (1268701); Sialic Acid Metabolism Pathway (1268721)
ncbi summary :
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]
uniprot summary :
NEU3: Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. Belongs to the glycosyl hydrolase 33 family. Protein type: Hydrolase; Glycan Metabolism - other glycan degradation; Lipid Metabolism - sphingolipid; EC 3.2.1.18. Chromosomal Location of Human Ortholog: 11q13.5. Cellular Component: cytoplasm; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane. Molecular Function: alpha-sialidase activity; exo-alpha-sialidase activity. Biological Process: carbohydrate metabolic process; ganglioside catabolic process; glycosphingolipid metabolic process; oligosaccharide catabolic process
size1 :
1 Pair (Sufficient for 5 x96 well plates)