antibody

Mouse anti-human TIMP1 monoclonal antibody

MBS7041578

1 mg

195 USD

monoclonal

mouse

nonconjugated

ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Mouse anti-human TIMP1 monoclonal antibody

[TIMP1]

[TIMP1; TIMP metallopeptidase inhibitor 1, isoform CRA_a; metalloproteinase inhibitor 1; TIMP metallopeptidase inhibitor 1; TIMP metallopeptidase inhibitor 1, isoform CRA_a]

[TIMP1]

[TIMP1; TIMP1; EPA; EPO; HCI; CLGI; TIMP; TIMP-1]

Q6FGX5_HUMAN

Monoclonal

Mouse

207

Human TIMP1

>95% by Caprylic Acid Ammonium Sulfate Precipitation purified

Liquid

Shipped at 4 degree C Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

ELISA (EIA), Immunohistochemistry (IHC), Chemiluminescent Immunoassay (CLIA)

Note: Applications are user defined. Product is developed as raw material and quality control tested in house, data is not provided on the data sheet. The researcher needs to establish and confirm the suitability of the product for their application. Testing data may be available for this product regarding applications and assays the lab developed, please inquire.

Liver Function & Injury

Mouse monoclonal antibody to Human TIMP1

49456917

CAG46779.1

Q6FGX5

23,171 Da

Activation Of Matrix Metalloproteinases Pathway (1270258); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); HIF-1 Signaling Pathway (695200); Hemostasis Pathway (1269340); IL6-mediated Signaling Events Pathway (137932); Matrix Metalloproteinases Pathway (198900); Platelet Activation, Signaling And Aggregation Pathway (1269350); Platelet Degranulation Pathway (1269367); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1269365)

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]

1 mg

195 USD

2 mg

340

5 mg

800