catalog number :
MBS704059
products type :
ELISA Kit
products full name :
Human glycoprotein 130, gp130 ELISA Kit
products short name :
glycoprotein 130, gp130
products name syn :
Human glycoprotein 130; gp130 ELISA KIT; Human glycoprotein 130; gp130
other names :
gp130, partial; Gp130; interleukin-6 receptor subunit beta; CD130 antigen; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; membrane glycoprotein gp130; gp130, oncostatin M receptor; interleukin receptor beta chain; oncostatin-M receptor subunit alpha; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; interleukin 6 signal transducer; Gp130
products gene name :
gp130
other gene names :
IL6ST; gp130; CD130; GP130; CDW130; IL-6RB
uniprot entry name :
Q13514_HUMAN
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Detection Range: 0.938ng/ml-60ng/ml. Detection Wavelength: 450 nm. Sensitivity: 0.516ng/ml
other info2 :
Sample Volume: 50-100ul. Protein Biological Process 1: Cytokine
ncbi acc num :
AAB35921.1
ncbi mol weight :
5,511 Da
ncbi pathways :
Adipogenesis Pathway 198832!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL-6 Signaling Pathway 198864!!IL27-mediated Signaling Events Pathway 137929!!IL6-mediated Signaling Events Pathway 137932!!Immune System Pathway 106386!!Interleukin-11 Signaling Pathway 698753!!Interleukin-6 Signaling Pathway 205111
ncbi summary :
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]