product summary
Loading...
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human T-H glycoprotein, THP ELISA Kit
catalog :
MBS703342
quantity :
96 Strip Wells
price :
850 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS703342
products type :
ELISA Kit
products full name :
Human T-H glycoprotein, THP ELISA Kit
products short name :
uromodulin
products name syn :
Human T-H glycoprotein; THP ELISA Kit; ADMCKD2; FJHN; HNFJ; HNFJ1; MCKD2; THGP; THP; Tamm-Horsfall glycoprotein; uromodulin (uromucoid; Tamm-Horsfall glycoprotein) ; uromucoid; uromodulin
other names :
uromodulin isoform a preproprotein; Uromodulin; uromodulin; uromucoid; Tamm-Horsfall urinary glycoprotein; uromodulin; Tamm-Horsfall urinary glycoprotein; THP
products gene name :
UMOD
other gene names :
UMOD; UMOD; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2; THP
uniprot entry name :
UROM_HUMAN
reactivity :
Human
sequence length :
640
specificity :
This assay has high sensitivity and excellent specificity for detection of Human UMOD. No significant cross-reactivity or interference between Human UMOD and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm
other info2 :
Sample Volume: 50-100ul
ncbi gi num :
56550049
ncbi acc num :
NP_001008390.1
ncbi gb acc num :
NM_001008389.2
uniprot acc num :
P07911
ncbi mol weight :
69,761 Da
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
ncbi summary :
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
uniprot summary :
Function: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelial.1 PublicationManual assertion based on experiment in:Ref.10
size :
96 Strip Wells
price :
850 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!