ELISA/assay

Rat Triggering Receptor Expresses on Myeloid Cells-1, TREM-1 ELISA Kit

MBS703235

48-Strip-Wells

565 USD

ELISA Kit

Rat Triggering Receptor Expresses on Myeloid Cells-1, TREM-1 ELISA Kit

Triggering Receptor Expresses on Myeloid Cells-1, TREM-1

Rat Triggering Receptor Expresses on Myeloid Cells-1; TREM-1 ELISA Kit; Triggering Receptor Expresses on Myeloid Cells-1; TREM-1

triggering receptor expressed on myeloid cells 1 isoform 1; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on myeloid cells 1, isoform CRA_a; cDNA, FLJ93589, Homo sapiens triggering receptor expressed on myeloid cells 1 (TREM1), mRNA

TREM-1

TREM1; TREM1; CD354; TREM-1; hCG_32869

Q38L15_HUMAN

Rat

234

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml-2000 pg/ml. Sensitivity: 7.8 pg/ml

Detection Wavelength: 450 nm. Sample Volume: 50-100ul

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TREM-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TREM-1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TREM-1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TREM-1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

8924262

NP_061113.1

NM_018643.3

Q38L15

26,387 Da

Cell Surface Interactions At The Vascular Wall Pathway (106062); DAP12 Interactions Pathway (685549); Hemostasis Pathway (106028); Immune System Pathway (106386); Innate Immune System Pathway (106387)

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 6p21.1. Cellular Component: extracellular region; plasma membrane; integral to membrane. Molecular Function: receptor activity. Biological Process: neutrophil chemotaxis; innate immune response; cytokine secretion during immune response; blood coagulation; chemokine metabolic process; leukocyte migration; humoral immune response

48-Strip-Wells

565 USD

96-Strip-Wells

810

5x96-Strip-Wells

2750

10x96-Strip-Wells

5150