catalog number :
MBS703165
products type :
ELISA Kit
products full name :
Rat Calcitonin, CT ELISA Kit
products short name :
calcitonin-related polypeptide alpha
products name syn :
Rat Calcitonin; CT ELISA Kit; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; MGC126648; calcitonin 1; calcitonin gene-related peptide 1; calcitonin/calcitonin-related polypeptide; alpha; katacalcin; calcitonin-related polypeptide alpha
other names :
calcitonin gene-related peptide 1 isoform Cgrp preproprotein; Calcitonin gene-related peptide 1; calcitonin gene-related peptide 1; CGRP-I; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; calcitonin-related polypeptide alpha; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I
products gene name :
CALCA
other gene names :
Calca; Calca; CAL6; CGRP; Cal1; Calc; RATCAL6; calcitonin; Calc; CGRP-I
uniprot entry name :
CALCA_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of rat CT. No significant cross-reactivity or interference between rat CT and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma and and and tissue homogenates. Assay Type: Sandwich. Detection Range: 1.56 pg/ml -100 pg/ml. Sensitivity: 0.39 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CT has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CT present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CT is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CT bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001029127.1
ncbi gb acc num :
NM_001033955.1
ncbi mol weight :
13,948 Da
ncbi pathways :
Amyloids Pathway (1010489); Calcitonin-like Ligand Receptors Pathway (1010190); Class B/2 (Secretin Family Receptors) Pathway (1010189); Disease Pathway (1010484); G Alpha (s) Signalling Events Pathway (1010194); GPCR Downstream Signaling Pathway (1010193); GPCR Ligand Binding Pathway (1010163); Myometrial Relaxation And Contraction Pathways (198465); Signal Transduction Pathway (1010015); Signaling By GPCR Pathway (1010162)
ncbi summary :
an inhibitor of lactotroph function and a potent vasodilator [RGD, Feb 2006]
uniprot summary :
Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
size4 :
10x96-Strip-Wells