product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Angiotensin converting enzyme, ACE ELISA Kit
catalog :
MBS703086
quantity :
48-Strip-Wells
price :
605 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS703086
products type :
ELISA Kit
products full name :
Rat Angiotensin converting enzyme, ACE ELISA Kit
products short name :
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
products name syn :
Rat Angiotensin converting enzyme; ACE ELISA Kit; ACE1; CD143; DCP; DCP1; MGC26566; MVCD3; CD143 antigen; angiotensin I converting enzyme 1; angiotensin converting enzyme; somatic isoform; carboxycathepsin; dipeptidyl carboxypeptidase 1; kininase II; pep; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
other names :
angiotensin-converting enzyme isoform 1; Angiotensin-converting enzyme; angiotensin-converting enzyme; kininase II; peptidyl dipeptidase i; dipeptidyl carboxypeptidase I; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen: CD143Cleaved into the following chain:Angiotensin-converting enzyme, soluble form
products gene name :
ACE
other gene names :
ACE; ACE; DCP1; ACE
uniprot entry name :
ACE_RABIT
reactivity :
Rat
sequence length :
1310
specificity :
This assay has high sensitivity and excellent specificity for detection of rat ACE. No significant cross-reactivity or interference between rat ACE and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Quantitative Competitive. Sensitivity: Typically less than 19.5 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with ACE. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for ACE. The competitive inhibition reaction is launched between with pre-coated ACE and ACE in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of ACE in the samples. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
126723380
ncbi acc num :
NP_001075864.1
ncbi gb acc num :
NM_001082395.1
uniprot acc num :
P12822
ncbi mol weight :
150,406 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety . Catalytic activity: Release of a C-terminal dipeptide, oligopeptide- -Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II. Cofactor: Binds 2 zinc ions per subunit. Isoform Testis-specific only binds 1 zinc ion per subunit . Enzyme regulation: Strongly activated by chloride. Specifically inhibited by lisinopril.1 PublicationManual assertion based on experiment in:Ref.11
size1 :
48-Strip-Wells
price1 :
605 USD
size2 :
96-Strip-Wells
price2 :
870
size3 :
5x96-Strip-Wells
price3 :
2950
size4 :
10x96-Strip-Wells
price4 :
5535
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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