catalog number :
MBS703050
products type :
ELISA Kit
products full name :
Mouse Tumor necrosis factor soluble receptor I , TNFsR-I ELISA Kit
products short name :
tumor necrosis factor receptor superfamily, member 1A
products name syn :
Mouse Tumor necrosis factor soluble receptor I; TNFsR-I ELISA KIT; CD120a; FPF; MGC19588; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor re; Mouse Tumor necrosis factor soluble receptor I; TNFsR-I
other names :
tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily member 1A; p60; TNF-RI; TNFR-I; TNF-alpha-R1; TNF receptor alpha chain; tumor necrosis factor receptor 1; tumor necrosis factor receptor type I; tumor necrosis factor receptor superfamily, member 1a; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD_antigen: CD120a
products gene name :
TNFRSF1A
other gene names :
Tnfrsf1a; Tnfrsf1a; FPF; p55; TNF-R; TNFAR; TNFRI; Tnfr1; p55-R; CD120a; TNF-R1; TNFR60; Tnfr-2; TNF-R-I; TNF-R55; TNFRp55; TNF-alphaR1; TNFalpha-R1; Tnfr-1; Tnfr1; TNF-R1; TNF-RI; TNFR-I
uniprot entry name :
TNR1A_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of Mouse TNFRSF1A. No significant cross-reactivity or interference between Mouse TNFRSF1A and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.625 pg/ml-1000 pg/ml. Sensitivity: 1.261 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Tumor marker
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TNFsR-I has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TNFsR-I present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFsR-I is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFsR-I bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_035739.2
ncbi gb acc num :
NM_011609.4
ncbi mol weight :
50,130 Da
ncbi pathways :
Adipocytokine Signaling Pathway (83290); Adipocytokine Signaling Pathway (505); Alzheimer's Disease Pathway (83294); Alzheimer's Disease Pathway (509); Amyotrophic Lateral Sclerosis (ALS) Pathway (83296); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (198339); Apoptosis Pathway (83257); Apoptosis Pathway (470); Apoptosis Pathway (970512)
uniprot summary :
Function: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis
size3 :
10x96-Strip-Wells