product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Thyroglobulin, TG ELISA Kit
catalog :
MBS702965
quantity :
96 Strip Wells
price :
670 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS702965
products type :
ELISA Kit
products full name :
Human Thyroglobulin, TG ELISA Kit
products short name :
thyroglobulin
products name syn :
Human Thyroglobulin; TG ELISA Kit; AITD3; TGN; ; thyroglobulin
other names :
thyroglobulin; Thyroglobulin; thyroglobulin; thyroglobulin
products gene name :
TG
other gene names :
TG; TG; TGN; AITD3; Tg
uniprot entry name :
THYG_HUMAN
reactivity :
Human
sequence length :
2768
specificity :
This assay has high sensitivity and excellent specificity for detection of Human TG. No significant cross-reactivity or interference between Human TG and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm
other info2 :
Sample Volume: 50-100ul. Protein Biological Process 1: Biosynthesis/Metabolism. Protein Biological Process 3: Thyroid hormones biosynthesis
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. An antibody specific to TG has been pre-coated onto a microplate. Standards or samples are added to the appropriate microtiter plate wells with biotin-conjugated TG and incubated. A competitive inhibition reaction is launched between TG (Standards or samples) and Biotin-conjugated TG with the pre-coated antibody specific for TG. The more amount of TG in samples, the less antibody bound by Biotin-conjugated TG. Then Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The substrate solutions are added to the wells, respectively. And the color develops in opposite to the amount of TG in the sample. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
55770862
ncbi acc num :
NP_003226.4
ncbi gb acc num :
NM_003235.4
uniprot acc num :
P01266
ncbi mol weight :
304,790 Da
ncbi pathways :
Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!Thyroid Hormone Synthesis Pathway 835410!!Thyroid Hormone Synthesis Pathway 839541!!Thyroxine (Thyroid Hormone) Production Pathway 920992
ncbi summary :
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
uniprot summary :
Function: Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).
size :
96 Strip Wells
price :
670 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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