Mouse A Disintegrin And Metalloprotease 8, ADAM8 ELISA Kit | MyBioSource MBS702561 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse A Disintegrin And Metalloprotease 8, ADAM8 ELISA Kit

catalog :

MBS702561

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS702561

products type :

ELISA Kit

products full name :

Mouse A Disintegrin And Metalloprotease 8, ADAM8 ELISA Kit

products short name :

ADAM metallopeptidase domain 8

products name syn :

Mouse A Disintegrin And Metalloprotease 8; ADAM8 ELISA Kit; CD156; MGC134985; MS2; a disintegrin and metalloproteinase domain 8; cell surface antigen MS2; disintegrin and metalloproteinase domain-containing protein 8; human leukocyte differentiation antigen; ADAM metallopeptidase domain 8

other names :

disintegrin and metalloproteinase domain-containing protein 8 isoform 1; Disintegrin and metalloproteinase domain-containing protein 8; disintegrin and metalloproteinase domain-containing protein 8; ADAM 8; cell surface antigen MS2; macrophage cysteine-rich glycoprotein; a disintegrin and metalloprotease domain 8; a disintegrin and metalloprotease domain (ADAM) 8; a disintegrin and metallopeptidase domain 8; Cell surface antigen MS2; Macrophage cysteine-rich glycoprotein; CD_antigen: CD156a

products gene name :

ADAM8

other gene names :

Adam8; Adam8; MS2; CD156; CD156a; E430039A18Rik; Ms2; ADAM 8

uniprot entry name :

ADAM8_MOUSE

reactivity :

Mouse

sequence length :

826

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse ADAM8. No significant cross-reactivity or interference between Mouse ADAM8 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: 15.6 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Introduction: ADAM metallopeptidase domain 8, also known as ADAM8, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ADAM8. Standards or samples are then added to the appropriate microtiter plate wells with a biotin conjugated antibody preparation specific for ADAM8 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain ADAM8, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of ADAM8 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

6680642

ncbi acc num :

NP_031429.1

ncbi gb acc num :

NM_007403.2

uniprot acc num :

Q05910

ncbi mol weight :

90,046 Da

ncbi pathways :

Degradation Of The Extracellular Matrix Pathway (1001028); Extracellular Matrix Organization Pathway (1001015)

ncbi summary :

This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]

uniprot summary :

Function: Possible involvement in extravasation of leukocytes. Cofactor: Binds 1 zinc ion per subunit Inferred.

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage