Mouse soluble interleukin-1 receptor II, IL-1sRII ELISA Kit | MyBioSource MBS702493 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse soluble interleukin-1 receptor II, IL-1sRII ELISA Kit

catalog :

MBS702493

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS702493

products type :

ELISA Kit

products full name :

Mouse soluble interleukin-1 receptor II, IL-1sRII ELISA Kit

products short name :

interleukin 1 receptor, type II

products name syn :

Mouse soluble interleukin-1 receptor II; IL-1sRII ELISA kit; CD121b; IL1RB; MGC47725; antigen CDw121b; type II interleukin-1 receptor; beta; interleukin 1 receptor; type II

other names :

interleukin-1 receptor type 2; Interleukin-1 receptor type 2; interleukin-1 receptor type 2; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; IL-1 type II receptor; IL-1 receptor beta chain; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; interleukin 1 receptor, type II; CD121 antigen-like family member B; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD_antigen: CD121bCleaved into the following 2 chains:Interleukin-1 receptor type 2, membrane form; mIL-1R2; mIL-1RII; Interleukin-1 receptor type 2, soluble form; sIL-1R2; sIL-1RII

products gene name :

IL1R2

other gene names :

Il1r2; Il1r2; CD121b; Il1r-2; Il-1r2; Il1rb; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII

uniprot entry name :

IL1R2_MOUSE

reactivity :

Mouse

sequence length :

410

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse IL1R2. No significant cross-reactivity or interference between Mouse IL1R2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.235 ng/ml-15 ng/ml. Sensitivity: 0.058 ng/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

For Sample For the quantitative determination of mouse soluble interleukin-1 receptor ? (IL-1sR ) c ? oncentrations in serum, plasma, tissue homogenates. concentrations in serum, plasma, tissue homo enates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL-1sR? has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-1sR? present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-1sR? is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-1sR? bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

6754330

ncbi acc num :

NP_034685.1

ncbi gb acc num :

NM_010555.4

uniprot acc num :

P27931

ncbi mol weight :

45,645 Da

ncbi pathways :

Amoebiasis Pathway (167330); Amoebiasis Pathway (167191); Cytokine Signaling In Immune System Pathway (970814); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489); IL-1 Signaling Pathway (198360)

uniprot summary :

Function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors 2 PublicationsManual assertion based on experiment in:Ref.2

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage