catalog number :
MBS702353
products type :
ELISA Kit
products full name :
Fish Interleukin 6, IL-6 ELISA Kit
products short name :
Interleukin 6, IL-6
products name syn :
Fish Interleukin 6; IL-6 ELISA Kit; Interleukin 6; IL-6
other names :
interleukin-6; Interleukin-6; interleukin-6; IL-6; Interleukin 6 (interferon, beta 2); interleukin 6
products gene name :
IL-6
other gene names :
Il6; Il6; ILg6; Ifnb2; Il-6; IL-6
uniprot entry name :
IL6_RAT
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Sample Type: serum, plasma, tissue homogenates. Detection Range: 12.5 pg/ml-200 pg/ml. Detection Wavelength: 450 nm. Sensitivity: 6.25 pg/ml
other info2 :
Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. An antibody specific to IL-6 has been pre-coated onto a microplate. Standards or samples are added to the appropriate microtiter plate wells with biotin-conjugated IL-6 and incubated. A competitive inhibition reaction is launched between IL-6 (Standards or samples) and Biotin-conjugated IL-6 with the pre-coated antibody specific for IL-6. The more amount of IL-6 in samples, the less antibody bound by Biotin-conjugated IL-6. Then Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The substrate solutions are added to the wells, respectively. And the color develops in opposite to the amount of IL-6 in the sample. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_036721.1
ncbi gb acc num :
NM_012589.2
ncbi mol weight :
24,357 Da
ncbi pathways :
Adipogenesis Pathway 198479!!African Trypanosomiasis Pathway 194377!!African Trypanosomiasis Pathway 194323!!Amoebiasis Pathway 167311!!Amoebiasis Pathway 167191!!Androgen Receptor Signaling Pathway 198529!!Cellular Senescence Pathway 1010386!!Cellular Responses To Stress Pathway 1010374!!Chagas Disease (American Trypanosomiasis) Pathway 147806!!Chagas Disease (American Trypanosomiasis) Pathway 147795
ncbi summary :
a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 2006]
uniprot summary :
Function: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation