ELISA/assay

Human Relaxin, RLN ELISA Kit

MBS702180

48-Strip-Wells

565 USD

ELISA Kit

Human Relaxin, RLN ELISA Kit

relaxin 1

Human Relaxin; RLN ELISA Kit; H1; RLXH1; bA12D24.3.1; bA12D24.3.2; preprorelaxin H1; prorelaxin; relaxin H1; relaxin 1

prorelaxin H1 preproprotein; Prorelaxin H1; prorelaxin H1; preprorelaxin H1; relaxin 1

RLN1

RLN1; RLN1; H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2

REL1_HUMAN

Human

185

This assay has high sensitivity and excellent specificity for detection of Human RLN1. No significant cross-reactivity or interference between Human RLN1 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 6.25 pg/ml-400 pg/ml. Sensitivity: 1.56 pg/ml

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

For Sample: For the quantitative determination of human relaxin (RLN) concentrations in serum, plasma, tissue homogenates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for relaxin has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any relaxin present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for relaxin is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of relaxin bound in the initial step. The color development is stopped and the intensity of the color is measured.

5902052

NP_008842.1

NM_006911.3

P04808

21,146 Da

Androgen Receptor Signaling Pathway (198806); Myometrial Relaxation And Contraction Pathways (198759)

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]

Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

48-Strip-Wells

565 USD

96-Strip-Wells

810

5x96-Strip-Wells

2750

10x96-Strip-Wells

5150