Human A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit | MyBioSource MBS702130 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit

catalog :

MBS702130

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS702130

products type :

ELISA Kit

products full name :

Human A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit

products short name :

ADAM metallopeptidase domain 33

products name syn :

Human A Disintegrin And Metalloprotease 33; ADAM33 ELISA Kit; RP5-964F7.2; C20orf153; DJ964F7.1; DKFZp434K0521; FLJ35308; FLJ36751; MGC149823; MGC71889; a disintegrin and metalloprotease 33; a disintegrin and metalloproteinase domain 33; disintegrin and reprolys; ADAM metallopeptidase domain 33

other names :

disintegrin and metalloproteinase domain-containing protein 33 isoform gamma preproprotein; Disintegrin and metalloproteinase domain-containing protein 33; disintegrin and metalloproteinase domain-containing protein 33; ADAM 33; a disintegrin and metalloprotease 33; a disintegrin and metalloproteinase domain 33; disintegrin and reprolysin metalloproteinase family protein; ADAM metallopeptidase domain 33

products gene name :

ADAM33

other gene names :

ADAM33; ADAM33; C20orf153; DJ964F7.1; C20orf153; UNQ873/PRO1891; ADAM 33

uniprot entry name :

ADA33_HUMAN

reactivity :

Human

sequence length :

812

specificity :

This assay has high sensitivity and excellent specificity for detection of Human ADAM33. No significant cross-reactivity or interference between Human ADAM33 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Assay Type: Sandwich. Detection Range: 31.2 pg/ml-2000 pg/ml. Sensitivity: 8 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAM33 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAM33 present is bound by the immobilized antibody. After removing anyunbound substances, a biotin-conjugated antibody specific for ADAM33 is added to the wells.After washing,avidin conjugated Horseradish Peroxidase (HRP) is added to the wells.Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added tothe wells and color develops in proportion to the amount of ADAM33 bound in the initial step. The colordevelopment is stopped and the intensity of the color is measured.

ncbi gi num :

540344525

ncbi acc num :

NP_001269376.1

ncbi gb acc num :

NM_001282447.1

uniprot acc num :

Q9BZ11

ncbi mol weight :

87,739 Da

ncbi pathways :

Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)

ncbi summary :

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

uniprot summary :

ADAM33: Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: integral to membrane. Molecular Function: zinc ion binding; metalloendopeptidase activity. Biological Process: proteolysis

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage