product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Interleukin 1 receptor antagonist, IL-1ra ELISA Kit
catalog :
MBS701989
quantity :
48-Strip-Wells
price :
390 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS701989
products type :
ELISA Kit
products full name :
Human Interleukin 1 receptor antagonist, IL-1ra ELISA Kit
products short name :
interleukin 1 receptor antagonist
products name syn :
Human Interleukin 1 receptor antagonist; IL-1ra ELISA kit; DIRA; ICIL-1RA; IL-1ra3; IL1F3; IL1RA; IRAP; MGC10430; MVCD4; IL1RN (IL1F3) ; OTTHUMP00000203730; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1r; interleukin 1 receptor antagonist
other names :
interleukin-1 receptor antagonist protein isoform 3; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist protein; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); interleukin 1 receptor antagonist; ICIL-1RA; IL1 inhibitor; INN: Anakinra
products gene name :
IL1RN
other gene names :
IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
uniprot entry name :
IL1RA_HUMAN
reactivity :
Human
sequence length :
159
specificity :
This assay has high sensitivity and excellent specificity for detection of Human IL1RN. No significant cross-reactivity or interference between Human IL1RN and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, cell culture supernates, tissue homogenates. Detection Range: 78 pg/ml-5000 pg/ml. Sensitivity: 19.5 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
ncbi gi num :
10835147
ncbi acc num :
NP_000568.1
ncbi gb acc num :
NM_000577.4
uniprot acc num :
P18510
ncbi mol weight :
20,055 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (366171); IL-1 Signaling Pathway (198908); IL1-mediated Signaling Events Pathway (137944); Immune System Pathway (106386); Interleukin-1 Signaling Pathway (160141); Leptin Signaling Pathway (672456); SIDS Susceptibility Pathways (198901); Signaling By Interleukins Pathway (160140)
ncbi summary :
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.1 PublicationManual assertion based on experiment in:Ref.17
size1 :
48-Strip-Wells
price1 :
390 USD
size2 :
96-Strip-Wells
price2 :
550
size3 :
5x96-Strip-Wells
price3 :
2140
size4 :
10x96-Strip-Wells
price4 :
3990
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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