Rabbit transforming growth factorbeta2, TGFbeta2 ELISA Kit | MyBioSource MBS701873 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rabbit transforming growth factorbeta2, TGFbeta2 ELISA Kit

catalog :

MBS701873

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS701873

products type :

ELISA Kit

products full name :

Rabbit transforming growth factorbeta2, TGFbeta2 ELISA Kit

products short name :

transforming growth factorbeta2, TGFbeta2

products name syn :

Rabbit transforming growth factorbeta2; TGFbeta2 ELISA Kit; transforming growth factorbeta2; TGFbeta2

other names :

transforming growth factor beta-2 isoform 1; Transforming growth factor beta-2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; BSC-1 cell growth inhibitor; prepro-transforming growth factor beta-2; glioblastoma-derived T-cell suppressor factor; transforming growth factor, beta 2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; PolyerginCleaved into the following chain:Latency-associated peptide; LAP

products gene name :

TGFbeta2

other gene names :

TGFB2; TGFB2; LDS4; TGF-beta2; TGF-beta-2; G-TSF; LAP

uniprot entry name :

TGFB2_HUMAN

reactivity :

Rabbit

sequence length :

442

specificity :

This assay has high sensitivity and excellent specificity for detection of rabbit TGFbeta2. No significant cross-reactivity or interference between rabbit TGFbeta2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Competitive. Detection Range: 3.12 ng/ml -50 ng/ml. Sensitivity: The minimum detectable dose of rabbit TGFbeta2 is typically less than 3.12 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest rabbit TGFbeta2 concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to TGFbeta2. Standards or samples are added to the appropriate microtiter plate wells with Biotin-conjugated TGFbeta2. A competitive inhibition reaction is launched between TGFbeta2 (Standards or samples) and Biotin-conjugated TGFbeta2 with the pre-coated antibody specific for TGFbeta2. The more amount of TGFbeta2 in samples, the less antibody bound by Biotin-conjugated TGFbeta2. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Substrate solution is added to the wells and the color develops in opposite to the amount of TGFbeta2 in the sample. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

208022653

ncbi acc num :

NP_001129071.1

ncbi gb acc num :

NM_001135599.2

uniprot acc num :

P61812

ncbi mol weight :

50,573 Da

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chronic Myeloid Leukemia Pathway (83116); Chronic Myeloid Leukemia Pathway (528); Colorectal Cancer Pathway (83106)

ncbi summary :

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]

uniprot summary :

Function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

615

size3 :

5x96-Strip-Wells

price3 :

2340

size4 :

10x96-Strip-Wells

price4 :

4370

more info or order :

MyBioSource product webpage