ELISA/assay

Mouse Programmed Death 1, PD-1 ELISA Kit

MBS701855

48-Strip-Wells

565 USD

ELISA Kit

Mouse Programmed Death 1, PD-1 ELISA Kit

programmed cell death 1

Mouse Programmed Death 1 (PD-1) ELISA Kit; CD279; PD1; SLEB2; hPD-1; hPD-l; ; programmed cell death 1

programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; mPD-1; protein PD-1; programmed cell death 1; CD_antigen: CD279

PDCD1

Pdcd1; Pdcd1; PD-1; Pdc1; Ly101; Pd1; Protein PD-1; mPD-1

PDCD1_MOUSE

Mouse

288

This assay has high sensitivity and excellent specificity for detection of mouse PD-1. No significant cross-reactivity or interference between mouse PD-1 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates, cell lysates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml-20 ng/ml. Sensitivity: 0.078 ng/ml.

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PD-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PD-1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PD-1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PD-1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

6679239

NP_032824.1

NM_008798.2

Q02242

31,842 Da

Adaptive Immune System Pathway (971210); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Costimulation By The CD28 Family Pathway (1001187); Immune System Pathway (971216); PD-1 Signaling Pathway (1001192); T Cell Receptor Signaling Pathway (83277); T Cell Receptor Signaling Pathway (491)

Function: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors

48-Strip-Wells

565 USD

96-Strip-Wells

810

5x96-Strip-Wells

2750

10x96-Strip-Wells

5150