Mouse CXC-chemokine receptor 4, CXCR4 ELISA Kit | MyBioSource MBS701736 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse CXC-chemokine receptor 4, CXCR4 ELISA Kit

catalog :

MBS701736

quantity :

96 Strip Wells

price :

850 USD

product information

catalog number :

MBS701736

products type :

ELISA Kit

products full name :

Mouse CXC-chemokine receptor 4, CXCR4 ELISA Kit

products short name :

chemokine (C-X-C motif) receptor 4

products name syn :

Mouse CXC-chemokine receptor 4 (CXCR4) ELISA Kit; CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; C-X-C chemokine receptor type 4; CD184 antigen; fusin; leukocyte-derived seven-transmembrane-domain receptor; lip; chemokine (C-X-C motif) receptor 4

other names :

C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; fusin; CXC-R4; CXCR-4; SDF-1 receptor; chemokine receptor 4; chemokine (C-X-C) receptor 4; pre-B-cell-derived chemokine receptor; stromal cell-derived factor 1 receptor; leukocyte-expressed seven-transmembrane-domain; leukocyte-derived seven transmembrane domain receptor; chemokine (C-X-C motif) receptor 4; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; Pre-B-cell-derived chemokine receptor; PB-CKR; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD_antigen: CD184

products gene name :

CXCR4

other gene names :

Cxcr4; Cxcr4; CD184; LESTR; Sdf1r; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1; Cmkar4; Lestr; Sdf1r; CXC-R4; CXCR-4; LESTR; PB-CKR; SDF-1 receptor

uniprot entry name :

CXCR4_MOUSE

reactivity :

Mouse

sequence length :

359

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse CXCR4. No significant cross-reactivity or interference between Mouse CXCR4 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Range: 9.4 pg/ml-600 pg/ml. Detection Wavelength: 450 nm. Sensitivity: 2.3 pg/ml

other info2 :

Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CXCR4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CXCR4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXCR4 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXCR4 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

116268123

ncbi acc num :

NP_034041.2

ncbi gb acc num :

NM_009911.3

uniprot acc num :

P70658

ncbi mol weight :

40,426 Da

ncbi pathways :

Axon Guidance Pathway 83262!!Axon Guidance Pathway 476!!Chemokine Receptors Bind Chemokines Pathway 1000944!!Chemokine Signaling Pathway 99271!!Chemokine Signaling Pathway 672435!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 1000942!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endocytosis Pathway 102286

uniprot summary :

Function: Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.3 PublicationsManual assertion based on experiment in:Ref.9

size :

96 Strip Wells

price :

850 USD