Human platelet membrane glycoprotein IV, GP-IV ELISA Kit | MyBioSource MBS701617 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human platelet membrane glycoprotein IV, GP-IV ELISA Kit

catalog :

MBS701617

quantity :

96 Strip Wells

price :

850 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS701617

products type :

ELISA Kit

products full name :

Human platelet membrane glycoprotein IV, GP-IV ELISA Kit

products short name :

CD36 molecule (thrombospondin receptor)

products name syn :

Human platelet membrane glycoprotein IV; GP-IV ELISA Kit; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3; CD36 antigen; CD36 antigen (collagen type I receptor; thrombospondin receptor) ; OTTHUMP00000207872; OTTHUMP00000207874; PAS-4 protein; cluster determinant 36; f; CD36 molecule (thrombospondin receptor)

other names :

platelet glycoprotein 4 isoform 1; Platelet glycoprotein 4; platelet glycoprotein 4; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor); Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD_antigen: CD36

products gene name :

CD36

other gene names :

CD36; CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; GP3B; GP4; FAT; GPIIIB; GPIV

uniprot entry name :

CD36_HUMAN

reactivity :

Human

sequence length :

472

specificity :

This assay has high sensitivity and excellent specificity for detection of Human CD36. No significant cross-reactivity or interference between Human CD36 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Sample Type: serum, plasma, tissue homogenates. Detection Range: 2.5 ng/ml-160 ng/ml. Detection Wavelength: 450 nm. Sensitivity: 0.625 ng/ml

other info2 :

Sample Volume: 50-100ul. Protein Biological Process 1: Cell Adhesion. Protein Biological Process 3: Cell adhesion

products description :

For Samples: For the quantitative determination of human platelet membrane glycoprotein ? (GP-?) concentrations in serum, plasma, tissue homogenates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GP-? has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GP-? present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GP-? is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GP-? bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

48375178

ncbi acc num :

NP_000063.2

ncbi gb acc num :

NM_000072.3

uniprot acc num :

P16671

ncbi mol weight :

53,053 Da

ncbi pathways :

AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Activated TLR4 Signalling Pathway 106400!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Antigen Processing-Cross Presentation Pathway 477122!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway 477123

ncbi summary :

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

uniprot summary :

Function: Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects.2 PublicationsManual assertion based on experiment in:Ref.19

size :

96 Strip Wells

price :

850 USD

more info or order :

MyBioSource product webpage