ELISA/assay

Human Ficolin 3, FCN3 ELISA Kit

MBS701581

96 Strip Wells

850 USD

ELISA Kit

Human Ficolin 3, FCN3 ELISA Kit

ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

Human Ficolin 3 (FCN3) ELISA Kit; FCNH; HAKA1; MGC22543; H-ficolin; collagen/fibrinogen domain-containing lectin 3 p35; collagen/fibrinogen domain-containing protein 3; ficolin 3; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

ficolin-3 isoform 1; Ficolin-3; ficolin-3; H-ficolin; ficolin 3; collagen/fibrinogen domain-containing protein 3; collagen/fibrinogen domain-containing lectin 3 p35; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); ficolin (collagen/fibrinogen domain containing) 3; Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; Hakata antigen

FCN3

FCN3; FCN3; FCNH; HAKA1; FCNH; HAKA1

FCN3_HUMAN

Human

299

This assay has high sensitivity and excellent specificity for detection of Human FCN3. No significant cross-reactivity or interference between Human FCN3 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm

Sample Volume: 50-100ul. Protein Biological Process 1: Complement. Protein Biological Process 3: Complement activation lectin pathway

27754776

NP_003656.2

NM_003665.2

O75636

32,903 Da

Complement Cascade Pathway 106405!!Creation Of C4 And C2 Activators Pathway 106407!!Ficolins Bind To Repetitive Carbohydrate Structures On The Target Cell Surface Pathway 833818!!Immune System Pathway 106386!!Initial Triggering Of Complement Pathway 106406!!Innate Immune System Pathway 106387!!Lectin Pathway Of Complement Activation 106408

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]

Function: May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.1 PublicationManual assertion based on experiment in:Ref.9

96 Strip Wells

850 USD