product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Angiotensin II Receptor 2 antibody, AT2R-Ab ELISA Kit
catalog :
MBS701565
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS701565
products type :
ELISA Kit
products full name :
Human Angiotensin II Receptor 2 antibody, AT2R-Ab ELISA Kit
products short name :
Angiotensin II Receptor 2 antibody, AT2R-Ab
products name syn :
Human Angiotensin II Receptor 2 antibody; AT2R-Ab ELISA Kit; Angiotensin II Receptor 2 antibody; AT2R-Ab
other names :
angiotensin II receptor type 2 subtype; Type-2 angiotensin II receptor; type-2 angiotensin II receptor; angiotensin II type-2 receptor; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; AT2
other gene names :
AGTR2; AGTR2; AT2; ATGR2; MRX88; AT2
uniprot entry name :
AGTR2_HUMAN
reactivity :
Human
sequence length :
363
specificity :
This assay has high sensitivity and excellent specificity for detection of human AT2R-Ab. No significant cross-reactivity or interference between human AT2R-Ab and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma. Assay Type: Sandwich. Detection Range: 0.312 U/ml -20 U/ml. Sensitivity: The minimum detectable dose of human AT2R-Ab is typically less than 0.078 U/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with AT2R. Standards and samples are pipetted into the wells with a biotin-conjugated AT2R and avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of AT2R-Ab bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
607812
ncbi acc num :
AAA61794.1
uniprot acc num :
P50052
ncbi mol weight :
41,184 Da
ncbi pathways :
ACE Inhibitor Pathway (198763); Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)
ncbi summary :
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010]
uniprot summary :
Function: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.1 PublicationManual assertion based on experiment in:Ref.18
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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