Human soluble tumor necrosis factor-related apoptosis inducing ligand, sTRAIL ELISA Kit | MyBioSource MBS701472 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human soluble tumor necrosis factor-related apoptosis inducing ligand, sTRAIL ELISA Kit

catalog :

MBS701472

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS701472

products type :

ELISA Kit

products full name :

Human soluble tumor necrosis factor-related apoptosis inducing ligand, sTRAIL ELISA Kit

products short name :

[tumor necrosis factor (ligand) superfamily, member 10]

products name syn :

[Human soluble tumor necrosis factor-related apoptosis inducing ligand; sTRAIL ELISA KIT; APO2L; Apo-2L; CD253; TL2; TRAIL; Apo-2 ligand; TNF-related apoptosis inducing ligand TRAIL; tumor necrosis factor (ligand) family; member 10; tumor necrosis factor apoptosis-inducing ligand splice var; tumor necrosis factor (ligand) superfamily; member 10]

other names :

[tumor necrosis factor ligand superfamily member 10 isoform 2; Tumor necrosis factor ligand superfamily member 10; tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; TNF-related apoptosis inducing ligand TRAIL; tumor necrosis factor (ligand) family, member 10; chemokine tumor necrosis factor ligand superfamily member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor (ligand) superfamily, member 10; Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253]

products gene name :

[TNFSF10]

other gene names :

[TNFSF10; TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L; APO2L; TRAIL; Apo-2L; Protein TRAIL]

uniprot entry name :

TNF10_HUMAN

reactivity :

Human

sequence length :

101

specificity :

This assay has high sensitivity and excellent specificity for detection of human STIM1. No significant cross-reactivity or interference between human STIM1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 47 pg/ml-3000 pg/ml. Sensitivity: 11.7 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for STIM1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any STIM1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for STIM1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of STIM1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

300193032

ncbi acc num :

NP_001177871.1

ncbi gb acc num :

NM_001190942.1

uniprot acc num :

P50591

ncbi mol weight :

32,509 Da

ncbi pathways :

Apoptosis Pathway (198797); Apoptosis Pathway (83060); Apoptosis Pathway (470); Apoptosis Pathway (105648); Apoptosis Modulation And Signaling Pathway (198822); Caspase-8 Activation By Cleavage Pathway (105654); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Death Receptor Signalling Pathway (105650); Dimerization Of Procaspase-8 Pathway (105655)

ncbi summary :

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

uniprot summary :

Function: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. Cofactor: Binds 1 zinc ion per trimer.

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

435

size3 :

96-Strip-Wells

price3 :

625

size4 :

5x96-Strip-Wells

price4 :

2595

size5 :

10x96-Strip-Wells

price5 :

4905

more info or order :

MyBioSource product webpage