product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Bovine Thrombin-antithrombin III Complex, TAT-III ELISA Kit
catalog :
MBS701364
quantity :
48-Strip-Wells
price :
565 USD
more info or order :
product information
catalog number :
MBS701364
products type :
ELISA Kit
products full name :
Bovine Thrombin-antithrombin III Complex, TAT-III ELISA Kit
products short name :
Thrombin-antithrombin III Complex, TAT-III
products name syn :
Bovine Thrombin-antithrombin III Complex; TAT-III ELISA Kit; Thrombin-antithrombin III Complex; TAT-III
other names :
tat-III; Protein Tat; Transactivating regulatory protein
products gene name :
TAT-III
other gene names :
tat
uniprot entry name :
TAT_SIVVT
reactivity :
Bovine
sequence length :
100
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Sensitivity: 1.56 pg/ml
other info2 :
Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with TAT-III. Standards or samples are then added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) -conjugated antibody preparation specific for TAT-III, mix well and incubated. The more the amount of TAT-III in samples, the less HRP- conjugated antibody preparation specific for TAT-III bound by pre-coated TAT-III. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. And the color develops in opposite to the amount of TAT-III in the sample. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
4469309
ncbi acc num :
CAA30661.1
uniprot acc num :
P05913
ncbi mol weight :
11,387 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II (RNA pol II) complex, thereby increasing the level of full-length transcripts. In the absence of Tat, the RNA Pol II generates short or non-processive transcripts that terminate at approximately 60 bp from the initiation site. Tat associates with the CCNT1/cyclin-T1 component of the P-TEFb complex (CDK9 and CCNT1), which promotes RNA chain elongation. This binding increases Tat's affinity for a hairpin structure at the 5'-end of all nascent viral mRNAs referred to as the transactivation responsive RNA element (TAR RNA) and allows Tat/P-TEFb complex to bind cooperatively to TAR RNA. The CDK9 component of P-TEFb and other Tat-activated kinases hyperphosphorylate the C-terminus of RNA Pol II that becomes stabilized and much more processive
size1 :
48-Strip-Wells
price1 :
565 USD
size2 :
96-Strip-Wells
price2 :
810
size3 :
5x96-Strip-Wells
price3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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