catalog number :
MBS701122
products type :
ELISA Kit
products full name :
Human glucose transporter 1, GLUT1 ELISA Kit
products short name :
solute carrier family 2 (facilitated glucose transporter) , member 1
products name syn :
Human glucose transporter 1 (GLUT1) ELISA kit; DYT17; DYT18; GLUT; GLUT1; MGC141895; MGC141896; PED; solute carrier family 2 (facilitated glucose transporter); member 1
other names :
solute carrier family 2, facilitated glucose transporter member 1; Solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, facilitated glucose transporter member 1; GLUT-1; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; human T-cell leukemia virus (I and II) receptor; solute carrier family 2 (facilitated glucose transporter), member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter
products gene name :
SLC2A1
other gene names :
SLC2A1; SLC2A1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS; GLUT1; GLUT-1
uniprot entry name :
GTR1_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of Human SLC2A1. No significant cross-reactivity or interference between Human SLC2A1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 9.4 pg/ml-600 pg/ml. Sensitivity: 2.35 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Transport. Protein Biological Process 3: Sugar transport
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GLUT1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GLUT1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GLUT1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GLUT1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_006507.2
ncbi gb acc num :
NM_006516.2
ncbi mol weight :
54,084 Da
ncbi pathways :
Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (906000); Defective BTD Causes Biotidinase Deficiency Pathway (906015); Defective CD320 Causes Methylmalonic Aciduria Pathway (906012); Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway (906001); Defective GIF Causes Intrinsic Factor Deficiency Pathway (906004); Defective HLCS Causes Multiple Carboxylase Deficiency Pathway (906014)
ncbi summary :
This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
uniprot summary :
Function: Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
size4 :
10x96-Strip-Wells