catalog number :
MBS701090
products type :
ELISA Kit
products full name :
Human squamous cell carcinoma antigen 1, SCCAg1 ELISA Kit
products short name :
serpin peptidase inhibitor, clade B (ovalbumin) , member 3
products name syn :
Human squamous cell carcinoma antigen 1 (SCCAg1) ELISA kit; HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; T4-A; serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 3; squamous cell carcinoma antigen 1; serpin peptidase inhibitor; clade B (ovalbumin); member 3
other names :
serpin B3; Serpin B3; serpin B3; protein T4-A; squamous cell carcinoma antigen 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1
products gene name :
SERPINB3
other gene names :
SERPINB3; SERPINB3; SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD; SCCA; SCCA1; SCCA-1
uniprot entry name :
SPB3_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human SCCAg1. No significant cross-reactivity or interference between human SCCAg1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.31 ng/ml -10 ng/ml. Sensitivity: The minimum detectable dose of human SCCAg1 is typically less than 0.16 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest human SCCAg1 concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SCCAg1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for SCCAg1. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SCCAg1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_008850.1
ncbi gb acc num :
NM_006919.2
ncbi mol weight :
44,565 Da
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191)
uniprot summary :
Function: May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).1 PublicationManual assertion based on experiment in:Ref.17
size4 :
10x96-Strip-Wells