product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat thrombomodulin, TM ELISA Kit
catalog :
MBS701052
quantity :
48-Strip-Wells
price :
605 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS701052
products type :
ELISA Kit
products full name :
Rat thrombomodulin, TM ELISA Kit
products short name :
thrombomodulin, TM
products name syn :
Rat thrombomodulin; TM ELISA Kit; thrombomodulin; TM
other names :
thrombomodulin; Thrombomodulin; thrombomodulin; fetomodulin; CD141 antigen; thrombomodulin; Fetomodulin; CD_antigen: CD141
products gene name :
TM
other gene names :
THBD; THBD; TM; THRM; AHUS6; BDCA3; CD141; THPH12; THRM; TM
uniprot entry name :
TRBM_HUMAN
reactivity :
Rat
sequence length :
575
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates and Cell lysates. Detection Range: 1.56 ng/ml-100 ng/ml. Sensitivity: 0.39 ng/ml
other info2 :
Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TM. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for TM and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain TM, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of TM in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi gi num :
339657
ncbi acc num :
AAB59508.1
uniprot acc num :
P07204
ncbi mol weight :
60,329 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); Common Pathway (106060); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway (169349)
ncbi summary :
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
size1 :
48-Strip-Wells
price1 :
605 USD
size2 :
96-Strip-Wells
price2 :
870
size3 :
5x96-Strip-Wells
price3 :
2950
size4 :
10x96-Strip-Wells
price4 :
5535
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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