catalog number :
MBS700987
products type :
ELISA Kit
products full name :
Mouse soluble interleukin-1 receptor I , IL-1sRI ELISA Kit
products short name :
interleukin 1 receptor, type I
products name syn :
Mouse soluble interleukin-1 receptor I; IL-1sRI ELISA kit; CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80; OTTHUMP00000161344; antigen CD121a; interleukin 1 receptor alpha; type I; interleukin receptor 1; interleukin 1 receptor; type I
other names :
interleukin-1 receptor type 1 isoform 1; Interleukin-1 receptor type 1; interleukin-1 receptor type 1; p80; IL-1R-1; IL-1RT1; IL-1RT-1; IL-1R-alpha; IL-1 receptor alpha chain; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor, type I; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80; CD_antigen: CD121aCleaved into the following 2 chains:Interleukin-1 receptor type 1, membrane form; mIL-1R1; mIL-1RI; Interleukin-1 receptor type 1, soluble form; sIL-1R1; sIL-1RI
products gene name :
IL1R1
other gene names :
Il1r1; Il1r1; IL-iR; CD121a; CD121b; IL-1R1; Il1r-1; Il-1r1; Il1ra; IL-1R-1; IL-1RT-1; IL-1RT1; IL-1R-alpha; mIL-1R1; mIL-1RI; sIL-1R1; sIL-1RI
uniprot entry name :
IL1R1_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of Mouse IL1R1. No significant cross-reactivity or interference between Mouse IL1R1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: 15.6 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL-1sRI has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-1sRI present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-1sRI is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-1sRI bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_032388.1
ncbi gb acc num :
NM_008362.2
ncbi mol weight :
66,698 Da
ncbi pathways :
Amoebiasis Pathway (167330); Amoebiasis Pathway (167191); Apoptosis Pathway (83257); Apoptosis Pathway (470); Apoptosis Signaling Pathway (522973); Cytokine Signaling In Immune System Pathway (970814); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889)
uniprot summary :
Function: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex
size4 :
10x96-Strip-Wells