product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Angiotensin converting enzyme 2, ACE2 ELISA Kit
catalog :
MBS700969
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS700969
products type :
ELISA Kit
products full name :
Rat Angiotensin converting enzyme 2, ACE2 ELISA Kit
products short name :
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
products name syn :
Rat Angiotensin converting enzyme 2; ACE2 ELISA Kit; ACEH; DKFZp434A014; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin converting enzyme-like protein; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
other names :
angiotensin-converting enzyme 2; Angiotensin-converting enzyme 2; angiotensin-converting enzyme 2; ACE-related carboxypeptidase; renal angiotensin-converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; ACE-related carboxypeptidaseCleaved into the following chain:Processed angiotensin-converting enzyme 2
products gene name :
ACE2
other gene names :
Ace2; Ace2
uniprot entry name :
ACE2_RAT
reactivity :
Rat
sequence length :
805
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat ACE2. No significant cross-reactivity or interference between Rat ACE2 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Detection Range: 1.56 IU/ml -100 IU/ml. Sensitivity: 0.39 IU/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to ACE2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for ACE2 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain ACE2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of ACE2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi gi num :
58865588
ncbi acc num :
NP_001012006.1
ncbi gb acc num :
NM_001012006.1
uniprot acc num :
Q5EGZ1
ncbi mol weight :
92,491 Da
ncbi pathways :
Metabolism Of Angiotensinogen To Angiotensins Pathway (1009775); Metabolism Of Proteins Pathway (1009706); Peptide Hormone Metabolism Pathway (1009772); Protein Digestion And Absorption Pathway (172816); Protein Digestion And Absorption Pathway (171868); Renin-angiotensin System Pathway (83467); Renin-angiotensin System Pathway (486)
ncbi summary :
enzyme peptidyl-dipeptidase; mouse homolog has a role in regulation of cardiac contractility and regulating Angiotensin 1 and 2 levels [RGD, Feb 2006]
uniprot summary :
Function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.1 PublicationManual assertion based on experiment in:Ref.2. Catalytic activity: Angiotensin II + H2O = angiotensin-1-7 + L-phenylalanine. Cofactor: Binds 1 zinc ion per subunit . Enzyme regulation: Activated by chloride and fluoride, but not bromide. Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril, enalaprilat.1 PublicationManual assertion based on experiment in:Ref.3
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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