Human Neural cell adhesion molecule ligand 1, NCAM-L1 ELISA Kit | MyBioSource MBS700933 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Neural cell adhesion molecule ligand 1, NCAM-L1 ELISA Kit

catalog :

MBS700933

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS700933

products type :

ELISA Kit

products full name :

Human Neural cell adhesion molecule ligand 1, NCAM-L1 ELISA Kit

products short name :

L1 cell adhesion molecule

products name syn :

Human Neural cell adhesion molecule ligand 1; NCAM-L1 ELISA Kit; CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAML1; S10; SPG1; OTTHUMP00000025992; OTTHUMP00000063091; antigen identified by monoclonal antibody R1; neural cell adhesion molecule L1; L1 cell adhesion molecule

other names :

neural cell adhesion molecule L1 isoform 1; Neural cell adhesion molecule L1; neural cell adhesion molecule L1; antigen identified by monoclonal antibody R1; L1 cell adhesion molecule; CD_antigen: CD171

products gene name :

L1CAM

other gene names :

L1CAM; L1CAM; S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1; CAML1; MIC5; N-CAM-L1; NCAM-L1

uniprot entry name :

L1CAM_HUMAN

reactivity :

Human

sequence length :

1257

specificity :

This assay has high sensitivity and excellent specificity for detection of human NCAM-L1. No significant cross-reactivity or interference between human NCAM-L1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 1.25 ng/ml -80 ng/ml. Sensitivity: The minimum detectable dose of human NCAM-L1 is typically less than 0.31 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Princple of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NCAM-L1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NCAM-L1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NCAM-L1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NCAM-L1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4557707

ncbi acc num :

NP_000416.1

ncbi gb acc num :

NM_000425.4

uniprot acc num :

P32004

ncbi mol weight :

140,003 Da

ncbi pathways :

Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Basigin Interactions Pathway (106065); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (106062); Developmental Biology Pathway (477129); Hemostasis Pathway (106028); Interaction Between L1 And Ankyrins Pathway (161005)

ncbi summary :

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]

uniprot summary :

Function: Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage