ELISA/assay

Human forkhead box P3, FoxP3 ELISA Kit

MBS700674

48-Strip-Wells

510 USD

ELISA Kit

Human forkhead box P3, FoxP3 ELISA Kit

forkhead box P3

Human forkhead box P3 (FoxP3) ELISA Kit; AIID; DIETER; IPEX; JM2; MGC141961; MGC141963; PIDX; XPID; FOXP3delta7; immune dysregulation; polyendocrinopathy; enteropathy; X-linked; immunodeficiency; polyendocrinopathy; enteropathy; X-linked; scu; forkhead box P3

forkhead box protein P3 isoform b; Forkhead box protein P3; forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; forkhead box P3; Scurfin

FOXP3

FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; IPEX; JM2

FOXP3_HUMAN

Human

396

This assay has high sensitivity and excellent specificity for detection of human FoxP3. No significant cross-reactivity or interference between human FoxP3 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma. Assay Type: Sandwich. Detection Range: 31.25 pg/ml -2000 pg/ml. Sensitivity: 7.81 pg/ml.

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FoxP3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FoxP3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FoxP3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FoxP3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

167466190

NP_001107849.1

NM_001114377.1

Q9BZS1

47,244 Da

Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); IL2 Signaling Events Mediated By STAT5 Pathway (137988); Inflammatory Bowel Disease (IBD) Pathway (842771); Inflammatory Bowel Disease (IBD) Pathway (842797)

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function: Probable transcription factor. Plays a critical role in the control of immune response.

48-Strip-Wells

510 USD

96-Strip-Wells

725

5x96-Strip-Wells

2565

10x96-Strip-Wells

4800