catalog number :
MBS7006080
products full name :
ABI3 Antibody
products short name :
[ABI3]
products name syn :
[ABI gene family member 3; ABI3; NESH; New molecule including SH3; Nesh]
other names :
[ABI gene family member 3 isoform 2; ABI gene family member 3; ABI gene family member 3; ABI family member 3; New molecule including SH3; Nesh]
products gene name :
[ABI3]
other gene names :
[ABI3; ABI3; NESH; SSH3BP3; NESH; Nesh]
uniprot entry name :
ABI3_HUMAN
reactivity :
Human, mouse
purity :
Affinity Purified
storage stability :
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant human ABI gene family member 3 protein
other info2 :
Conjugation: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160122 / sc-160123 / sc-160124
products description :
May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.
ncbi acc num :
NP_001128658.1
ncbi gb acc num :
NM_001135186.1
ncbi mol weight :
38,450 Da
ncbi summary :
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
uniprot summary :
ABI3: May inhibit tumor metastasis. In vitro, reduces cell motility. Belongs to the ABI family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 17q21.3. Cellular Component: cytoplasm; intracellular; lamellipodium; membrane. Molecular Function: protein binding. Biological Process: cell motility; peptidyl-tyrosine phosphorylation; regulation of cell migration