product summary
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company name :
MyBioSource
product type :
antibody
product name :
MRAP2 Antibody
catalog :
MBS7005526
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot. All lanes: MRAP2 antibody at 7ug/ml. Lane 1: Mouse brain tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to Rabbit IgG at 1/10000 dilution. Predicted band size: 24 kDa. Observed band size: 24 kDa.
image 2 :
Immunofluorescent analysis of U251 cells using MBS7005526 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
image 3 :
Immunohistochemistry of paraffin-embedded human lung tissue using MBS7005526 at dilution 1:100
product information
catalog number :
MBS7005526
products type :
Antibody
products full name :
MRAP2 Antibody
products short name :
[MRAP2]
products name syn :
[Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2), MRAP2, C6orf117]
other names :
[melanocortin-2 receptor accessory protein 2; Melanocortin-2 receptor accessory protein 2; melanocortin-2 receptor accessory protein 2; melanocortin 2 receptor accessory protein 2]
products gene name :
[MRAP2]
other gene names :
[MRAP2; MRAP2; BMIQ18; C6orf117; bA51G5.2; C6orf117; MC2R accessory protein 2]
uniprot entry name :
MRAP2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
purity :
>95%,Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Recommended dilution: . WB:1:1000-1:5000. IHC:1:20-1:200. IF:1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7005526 at dilution 1:100
other info1 :
Immunogen: Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA). Conjugate: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Species: Human. Research Area: Neuroscience
products description :
Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
ncbi gi num :
156523251
ncbi acc num :
NP_612418.2
ncbi gb acc num :
NM_138409.2
uniprot acc num :
Q96G30
uniprot summary :
MRAP2: Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo. Belongs to the MRAP family. Homodimer and heterodimer. Forms antiparallel homodimers and heterodimers with MRAP. Interacts with MC1R, MC2R, MC3R, MC4R and MC5R. Chromosomal Location of Human Ortholog: 6q14.2. Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; plasma membrane. Molecular Function: adrenocorticotropin hormone receptor binding; identical protein binding; protein binding; type 3 melanocortin receptor binding; type 4 melanocortin receptor binding; type 5 melanocortin receptor binding. Biological Process: energy reserve metabolic process; feeding behavior; positive regulation of cAMP biosynthetic process. Disease: Body Mass Index Quantitative Trait Locus 18
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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