product summary
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company name :
MyBioSource
product type :
antibody
product name :
RANBP2 Antibody; FITC conjugated
catalog :
MBS7005483
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
FITC
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS7005483
products type :
Antibody
products full name :
RANBP2 Antibody; FITC conjugated
products short name :
[RANBP2]
products name syn :
[E3 SUMO-protein ligase RanBP2; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2; RanBP2; p270; RANBP2; NUP358]
other names :
[E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase RanBP2; RAN binding protein 2; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2; RanBP2; p270]
products gene name :
[RANBP2]
other gene names :
[RANBP2; RANBP2; ANE1; TRP1; TRP2; ADANE; IIAE3; NUP358; NUP358; RanBP2]
uniprot entry name :
RBP2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
3224
purity :
>95%,Protein G purified
form :
Liquid. Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
storage stability :
Upon receipt store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant human E3 SUMO-protein ligase RanBP2 protein (2601-2802AA). Species: Homo Sapiens (Human). Research Area: Cell Biology
other info2 :
Conjugation: FITC. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15442 / sc-240825 / sc-28577
products description :
E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB.
ncbi gi num :
150418007
ncbi acc num :
NP_006258.3
ncbi gb acc num :
NM_006267.4
uniprot acc num :
P49792
ncbi pathways :
Antiviral Mechanism By IFN-stimulated Genes Pathway (1269316); Cell Cycle Pathway (1269741); Cell Cycle, Mitotic Pathway (1269763); Cellular Response To Heat Stress Pathway (1270421); Cellular Responses To Stress Pathway (1270414); Cytokine Signaling In Immune System Pathway (1269310); Disease Pathway (1268854); Export Of Viral Ribonucleoproteins From Nucleus Pathway (1269121); Gene Expression Pathway (1269649); Gene Silencing By RNA Pathway (1269719)
ncbi summary :
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008]
uniprot summary :
E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB.
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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