product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Osteoprotegerin, OPG ELISA Kit
catalog :
MBS700506
quantity :
48-Strip-Wells
price :
490 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS700506
products type :
ELISA Kit
products full name :
Rat Osteoprotegerin, OPG ELISA Kit
products short name :
tumor necrosis factor receptor superfamily, member 11b
products name syn :
Rat Osteoprotegerin; OPG ELISA KIT; MGC29565; OCIF; OPG; TR1; osteoclastogenesis inhibitory factor; osteoprotegerin; tumor necrosis factor receptor superfamily; member 11b
other names :
tumor necrosis factor receptor superfamily member 11B; Tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin; tumor necrosis factor receptor superfamily, member 11b; Osteoprotegerin
products gene name :
TNFRSF11B
other gene names :
Tnfrsf11b; Tnfrsf11b; Opg; Opg
uniprot entry name :
TR11B_RAT
reactivity :
Rat
sequence length :
401
specificity :
This assay has high sensitivity and excellent specificity for detection of rat OPG. No significant cross-reactivity or interference between rat OPG and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates, cell lysates cell lysates cell lysates cell lysates cell lysates cell lysates cell lysates . Assay Type: Sandwich. Detection Range: 125 pg/ml -8000 pg/ml. Sensitivity: The minimum detectable dose of rat OPG is typically less than 31.25 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for OPG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any OPG present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for OPG is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of OPG bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
6981306
ncbi acc num :
NP_037002.1
ncbi gb acc num :
NM_012870.2
uniprot acc num :
O08727
ncbi mol weight :
46,192 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460); Osteoblast Pathway (198455); Osteoclast Pathway (198474); Osteoclast Differentiation Pathway (193140); Osteoclast Differentiation Pathway (193096)
ncbi summary :
plays a role in the negative regulation of bone resorption by inhibiting formation of osteoclasts [RGD, Feb 2006]
uniprot summary :
Function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis
size1 :
48-Strip-Wells
price1 :
490 USD
size2 :
96-Strip-Wells
price2 :
690
size3 :
5x96-Strip-Wells
price3 :
2560
size4 :
10x96-Strip-Wells
price4 :
4790
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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