ELISA/assay

Human Kidney injury molecule 1, Kim-1 ELISA Kit

MBS700484

96-Strip-Wells

630 USD

ELISA Kit

Human Kidney injury molecule 1, Kim-1 ELISA Kit

Kidney injury molecule 1, Kim-1

Human Kidney injury molecule 1; Kim-1 ELISA Kit; HAVCR; HAVCR-1; KIM-1; KIM1; TIM-1; TIM1; TIMD1; T cell immunoglobin domain and mucin domain protein 1; kidney injury molecule 1; Human Kidney injury molecule 1; Kim-1

hepatitis A virus cellular receptor 1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1

Kim-1

HAVCR1; HAVCR1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1; KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1

HAVR1_HUMAN

Human

364

This assay has high sensitivity and excellent specificity for detection of human Kim-1. No significant cross-reactivity or interference between human Kim-1 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, urine, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml -20 ng/ml. Sensitivity: 0.043 ng/ml.

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for Kim-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Kim-1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for Kim-1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of Kim-1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

153085429

NP_001092884.1

NM_001099414.1

Q96D42

38,720 Da

Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)

The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

Function: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair.2 PublicationsManual assertion based on experiment in:Ref.1

96-Strip-Wells

630 USD

5x96-Strip-Wells

1955

10x96-Strip-Wells

3635