catalog number :
MBS700336
products type :
ELISA Kit
products full name :
Human placenta growth factor, PLGF ELISA Kit
products short name :
placental growth factor
products name syn :
Human placenta growth factor; PLGF ELISA kit; D12S1900; PGFL; PLGF; PlGF-2; SHGC-10760; placenta growth factor; placental growth factor; vascular endothelial growth factor-related protein; placental growth factor-like; placental growth factor
other names :
placenta growth factor isoform 2; Placenta growth factor; placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein; placental growth factor
other gene names :
PGF; PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; PGFL; PLGF; PlGF
uniprot entry name :
PLGF_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human PLGF. No significant cross-reactivity or interference between human PLGF and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma and tissue homogenates. Assay Type: Sandwich. Detection Range: 1.67 ng/ml -40 ng/ml. Sensitivity: 0.7 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<10%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PLGF has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for PLGF. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLGF bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001193941.1
ncbi gb acc num :
NM_001207012.1
ncbi mol weight :
24,789 Da
ncbi pathways :
Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979); Pathways In Cancer (83105); Rap1 Signaling Pathway (868086); Rap1 Signaling Pathway (878042); Ras Signaling Pathway (868085); Signal Transduction Pathway (477114)
ncbi summary :
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
uniprot summary :
Function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.1 PublicationManual assertion based on experiment in:Ref.8
size4 :
10x96-Strip-Wells