product summary
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company name :
MyBioSource
product type :
antibody
product name :
GBP5 Antibody
catalog :
MBS7002179
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot. All lanes: GBP5 antibody at 6ug/ml+ Mouse thymus tissue. Goat polyclonal to rabbit at 1/10000 dilution. Predicted band size: 67,56 kDa. Observed band size: 67 kDa.
image 2 :
Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7002179 at dilution of 1:100
product information
catalog number :
MBS7002179
products type :
Antibody
products full name :
GBP5 Antibody
products short name :
[GBP5]
products name syn :
[Guanylate-binding protein 5 (EC:3.6.5.-2 Publications; GBP5; UNQ2427/PRO4987; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5]
other names :
[guanylate-binding protein 5; Guanylate-binding protein 5; guanylate-binding protein 5; guanylate binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5]
products gene name :
[GBP5]
other gene names :
[GBP5; GBP5; GBP-5; GBP-5]
uniprot entry name :
GBP5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, mouse
sequence length :
586
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant Human Guanylate-binding protein 5 protein (321-500AA)
other info2 :
Conjugation: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160353 / sc-160354. Research Area: Immunology
products description :
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
ncbi gi num :
197333737
ncbi acc num :
NP_001127958.1
ncbi gb acc num :
NM_001134486.2
uniprot acc num :
Q96PP8
ncbi mol weight :
55,247 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Immune System Pathway (1269170); Interferon Signaling Pathway (1269311); Interferon Gamma Signaling Pathway (1269314)
uniprot summary :
GBP5: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle; Hydrolase. Chromosomal Location of Human Ortholog: 1p22.2. Cellular Component: cytoplasmic vesicle; Golgi membrane; membrane. Molecular Function: GTP binding; GTPase activity; identical protein binding; protein binding. Biological Process: inflammatory response; interleukin-1 beta secretion; metabolic process; positive regulation of innate immune response; protein homotetramerization
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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