Rabbit anti-human Stress-induced-phosphoprotein 1 polyclonal Antibody | MyBioSource MBS7000907 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit anti-human Stress-induced-phosphoprotein 1 polyclonal Antibody

catalog :

MBS7000907

quantity :

0.05 mg

price :

160 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot. All lanes: Stress-induced-phosphoprotein 1 antibody at 2ug/ml+Hela whole cell lysate. Secondary. Goat polyclonal to Rabbit IgG at 1/15000 dilution. Predicted band size: 63,69,60 kDa. Observed band size: 63 kDa.

image 2 :

Western blot. All lanes: STIP1 antibody at 10ug/ml. Lane 1: MCF7 whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: A549 whole cell lysate. Lane 4: HepG-2 whole cell lysate. Lane 5: PC-3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 63,69,60 kDa. Observed band size: 63 kDa.

image 3 :

Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS7000907 at dilution 1:100

product information

catalog number :

MBS7000907

products type :

Antibody

products full name :

Rabbit anti-human Stress-induced-phosphoprotein 1 polyclonal Antibody

products short name :

[Stress-induced-phosphoprotein 1]

products name syn :

[Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein)(Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive proteinIEF SSP 3521), STIP1]

other names :

[stress-induced-phosphoprotein 1 isoform a; Stress-induced-phosphoprotein 1; stress-induced-phosphoprotein 1; stress induced phosphoprotein 1; Hsc70/Hsp90-organizing protein; Hop; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521]

products gene name :

[STIP1]

other gene names :

[STIP1; STIP1; HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STI1; Hop]

uniprot entry name :

STIP1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse , Rat.

sequence length :

590

purity :

>95%, Protein G purified

form :

Liquid

storage stability :

Upon receipt store at 20°C or -80°C . Avoid repeated freeze.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Recommended dilution: . WB: 1:500-2000. IHC: 1:20-1:200

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7000907 at dilution 1:100

other info1 :

Immunogen: Recombinant human Stress-induced-phosphoprotein 1 protein (1-543AA). Relevance: Mediated the association of the molcular chaperones HSC70 and HSP90 (HSPCA and HSPCB). Research Area: Signal Transduction

other info2 :

Conjugation: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27962 / sc-27963 / sc-292778

products categories :

Signal Transduction

products description :

Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).

ncbi gi num :

544063423

ncbi acc num :

NP_001269581.1

ncbi gb acc num :

NM_001282652.1

uniprot acc num :

P31948

ncbi pathways :

Prion Diseases Pathway (101144); Prion Diseases Pathway (100065)

ncbi summary :

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

uniprot summary :

STI1: a protein that is apparently involved in the response to stress. Specifically interacts with the C-terminal tails of Hsp70 and Hsp90 via TPR1 and TPR2A domains. Deletion of STI1 reduces the activity of the glucocorticoid receptor, a Hsp90 target protein. Phosphorylated in vitro by p90RSK and casein kinase II. Protein type: Chaperone. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: Golgi apparatus; myelin sheath; nucleus; protein complex. Molecular Function: chaperone binding; Hsp70 protein binding; protein binding; protein C-terminus binding. Biological Process: response to stress

size1 :

0.05 mg

price1 :

160 USD

size2 :

0.1 mg

price2 :

235

more info or order :

MyBioSource product webpage