product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat soluble interleukin-1 receptor II, sIL-1RII ELISA Kit
catalog :
MBS700063
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS700063
products type :
ELISA Kit
products full name :
Rat soluble interleukin-1 receptor II, sIL-1RII ELISA Kit
products short name :
interleukin 1 receptor, type II
products name syn :
Rat soluble interleukin-1 receptor II; sIL-1RII ELISA kit; CD121b; IL1RB; MGC47725; antigen CDw121b; type II interleukin-1 receptor; beta; interleukin 1 receptor; type II
other names :
interleukin-1 receptor type 2; Interleukin-1 receptor type 2; interleukin-1 receptor type 2; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; interleukin 1 receptor, type II; CD121 antigen-like family member B; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD_antigen: CD121bCleaved into the following 2 chains:Interleukin-1 receptor type 2, membrane form; mIL-1R2; mIL-1RII; Interleukin-1 receptor type 2, soluble form; sIL-1R2; sIL-1RII
products gene name :
IL1R2
other gene names :
Il1r2; Il1r2; Il-1r2; Il1rb; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII
uniprot entry name :
IL1R2_RAT
reactivity :
Rat
sequence length :
416
specificity :
This assay has high sensitivity and excellent specificity for detection of rat sIL-1R II. No significant cross-reactivity or interference between rat sIL-1R II and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.156 ng/ml -10 ng/ml. Sensitivity: 0.039 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for sIL-1RII has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any sIL-1RII present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for sIL-1RII is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of sIL-1RII bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
16758836
ncbi acc num :
NP_446405.1
ncbi gb acc num :
NM_053953.1
uniprot acc num :
P43303
ncbi mol weight :
46,353 Da
ncbi pathways :
Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Cytokine Signaling In Immune System Pathway (1011036); Cytokine-cytokine Receptor Interaction Pathway (83443); Cytokine-cytokine Receptor Interaction Pathway (460); HTLV-I Infection Pathway (373894); HTLV-I Infection Pathway (373889); Hematopoietic Cell Lineage Pathway (83470); Hematopoietic Cell Lineage Pathway (489); IL-1 Signaling Pathway (198458)
ncbi summary :
receptor for IL-1 alpha and IL-1 beta [RGD, Feb 2006]
uniprot summary :
Function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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