catalog number :
MBS700058
products type :
ELISA Kit
products full name :
Human anti-Granulocyte-Macrophage Colony Stimulating Factor, GM-CSF antibody ELISA Kit
products short name :
anti-Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) antibody
products name syn :
Human anti-Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) antibody ELISA Kit; anti-Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) antibody
other names :
GM-CSF; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; Molgramostin; Sargramostim
other gene names :
CSF2; CSF2; GMCSF; GMCSF; GM-CSF; CSF
uniprot entry name :
CSF2_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human GM-CSF antibody. No significant cross-reactivity or interference between human GM-CSF antibody and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum. Assay Type: Sandwich. Detection Range: 0.625 ng/ml -40 ng/ml. Sensitivity: 0.156 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%.Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with GM-CSF. Standards and samples are pipetted into the wells with a biotin-conjugated GM-CSF and avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GM-CSF antibody bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
AAA52578.1
ncbi mol weight :
16,295 Da
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Calcium Signaling In The CD4+ TCR Pathway (137941); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493)
ncbi summary :
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
size4 :
10x96-Strip-Wells