product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Neurotrophin 4, NT-4 ELISA Kit
catalog :
MBS700037
quantity :
96 Strip Wells
price :
645 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS700037
products type :
ELISA Kit
products full name :
Rat Neurotrophin 4, NT-4 ELISA Kit
products short name :
neurotrophin 4
products name syn :
Rat Neurotrophin 4; NT-4 ELISA KIT; GLC10; GLC1O; NT-4/5; NT4; NT5; NTF5; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5; neurotrophin 5 (neurotrophin 4/5) ; neurotrophin 4
other names :
neurotrophin-4; Neurotrophin-4; neurotrophin-4; NT-4; NT-5; neurotrophin-5; neutrophic factor 4; Neurotrophin 5 (neurotrophin 4/5); neurotrophin 4; Neurotrophin-5; NT-5; Neutrophic factor 4
products gene name :
NTF4
other gene names :
Ntf4; Ntf4; NT4P; Ntf5; Nt4; Ntf5; NT-4; NT-5
uniprot entry name :
NTF4_RAT
reactivity :
Rat
sequence length :
209
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat NTF4. No significant cross-reactivity or interference between Rat NTF4 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Sample Type: serum, plasma and tissue homogenates. Detection Range: 47 pg/ml-3000 pg/ml. Detection Wavelength: 450 nm. Sensitivity: 11.75 pg/ml
other info2 :
Sample Volume: 50-100ul
products description :
Introduction: Neurotrophins are a family of proteins that induce the survival, development and function of neurons. They belong to a class of growth factors, secreted proteins, which are capable of signaling particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death - thus allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons. Neurotrophin-4 (NT-4) like BDNF, is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to NT-4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for NT-4 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain NT-4, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of NT-4 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi gi num :
31377533
ncbi acc num :
NP_037316.2
ncbi gb acc num :
NM_013184.3
uniprot acc num :
P34131
ncbi mol weight :
22,333 Da
ncbi pathways :
MAPK Signaling Pathway 198496!!MAPK Signaling Pathway 83440!!MAPK Signaling Pathway 456!!Neurotrophin Signaling Pathway 101112!!Neurotrophin Signaling Pathway 100064
ncbi summary :
promotes the survival of peripheral sensory and sympathetic neurons [RGD, Feb 2006]
uniprot summary :
Function: Could serve as a target-derived trophic factor for sensory and sympathetic neurons.
size :
96 Strip Wells
price :
645 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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