catalog number :
MBS7000285
products full name :
PGLYRP4 Antibody; FITC conjugated
products short name :
[PGLYRP4]
products name syn :
[Peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta; PGLYRP4; PGRPIB]
other names :
[peptidoglycan recognition protein 4; Peptidoglycan recognition protein 4; peptidoglycan recognition protein 4; peptidoglycan recognition protein 4; Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta]
products gene name :
[PGLYRP4]
other gene names :
[PGLYRP4; PGLYRP4; PGRPIB; SBBI67; PGRP-Ibeta; PGLYRPIbeta; PGRPIB; PGLYRPIbeta; PGRP-I-beta]
uniprot entry name :
PGRP4_HUMAN
purity :
>95%,Protein G purified
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant human Peptidoglycan recognition protein 4 protein (18-317AA). Research Area: Immunology
other info2 :
Conjugation: FITC. Storage Buffer: Preservative: 0.03% Proclin 300 . Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-55877 / sc-55882
products description :
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
ncbi acc num :
NP_065126.2
ncbi gb acc num :
NM_020393.3
ncbi summary :
Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
uniprot summary :
PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: extracellular region; intracellular; membrane. Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding. Biological Process: defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation during immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process