product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human thrombomodulin, TM ELISA Kit
catalog :
MBS700007
quantity :
48-Strip-Wells
price :
565 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS700007
products type :
ELISA Kit
products full name :
Human thrombomodulin, TM ELISA Kit
products short name :
thrombomodulin
products name syn :
Human thrombomodulin; TM ELISA Kit; AHUS6; CD141; THRM; TM; CD141 antigen; fetomodulin; thrombomodulin
other names :
thrombomodulin; Thrombomodulin; thrombomodulin; fetomodulin; CD141 antigen; thrombomodulin; Fetomodulin; CD_antigen: CD141
products gene name :
THBD
other gene names :
THBD; THBD; TM; THRM; AHUS6; BDCA3; CD141; THPH12; THRM; TM
uniprot entry name :
TRBM_HUMAN
reactivity :
Human
sequence length :
575
specificity :
This assay has high sensitivity and excellent specificity for detection of Human THBD. No significant cross-reactivity or interference between Human THBD and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Competitive. Detection Range: 15.6 pg/ml-1000 pg/ml. Sensitivity: 7.8 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Blood Coagulation. Protein Biological Process 3: Blood coagulation
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with TM. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for TM. The competitive inhibition reaction is launched between with pre-coated TM and TM in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of TM in the sample. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
4507483
ncbi acc num :
NP_000352.1
ncbi gb acc num :
NM_000361.2
uniprot acc num :
P07204
ncbi mol weight :
60,329 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); Common Pathway (106060); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway (169349)
ncbi summary :
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
size1 :
48-Strip-Wells
price1 :
565 USD
size2 :
96-Strip-Wells
price2 :
810
size3 :
5x96-Strip-Wells
price3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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