product summary
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company name :
MyBioSource
product type :
protein
product name :
Human PLGF-1
catalog :
MBS696135
quantity :
0.005 mg
price :
125 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS696135
products type :
Recombinant Protein
products full name :
Human PLGF-1
products short name :
[PLGF-1]
products name syn :
[Placenta Growth Factor-1- PIGF, PGF]
other names :
[Placenta growth factor]
products gene name :
[PLGF-1]
other gene names :
[PGF; PGFL; PLGF; PlGF]
uniprot entry name :
PLGF_HUMAN
host :
E Coli
sequence :
MLPAVPPQQ WALSAGNGS SEVEVVPFQ EVWGRSYCR ALERLVDVV SEYPSEVEH MFSPSCVSL LRCTGCCGD ENLHCVPVE TANVTMQLL KIRSGDRPS YVELTFSQH VRCECRPLR EKMKPERCG DAVPRR
purity :
>=95% as determined by SDS-PAGE gel and HPLC analyses.
form :
Sterile filtered through a 0.2 micron filter. Lyophilized from 10mM Sodium Phosphate, pH 7.5.
storage stability :
At -20 degree C
image1 heading :
Testing Data
other info1 :
Endotoxin: Endotoxin level is <0.1 ng/ug of protein (<1EU/ug). Protein Content: Verified by UV Spectroscopy and/or SDS-PAGE gel. Reconstitution: Centrifuge the vial prior to opening. Reconsitute in water to a concentreation of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.
products categories :
Cancer; Angiogenesis; Inflammation; Proliferation and Cell Cycle
products description :
PLGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PLGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains.
uniprot acc num :
P49763
uniprot summary :
PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity. Biological Process: response to drug; organ regeneration; female pregnancy; signal transduction; cellular response to hormone stimulus; positive regulation of angiogenesis; cell-cell signaling; ureteric bud branching; positive regulation of cell division; positive regulation of cell proliferation; response to hypoxia; positive regulation of endothelial cell proliferation; sprouting angiogenesis; cell differentiation; vascular endothelial growth factor receptor signaling pathway
size1 :
0.005 mg
price1 :
125 USD
size2 :
0.025 mg
price2 :
195
size3 :
0.1 mg
price3 :
505
size4 :
0.5 mg
price4 :
1410
size5 :
1 mg
price5 :
2320
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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