product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Human Eotaxin-3 (CCL26)
catalog :
MBS696019
quantity :
0.005 mg
price :
125 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS696019
products type :
Recombinant Protein
products full name :
Human Eotaxin-3 (CCL26)
products short name :
[Eotaxin-3]
products name syn :
[Recombinant Human Eotaxin-3 (CCL26)]
other names :
[C-C motif chemokine 26; C-C motif chemokine 26; C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26; chemokine (C-C motif) ligand 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1]
products gene name :
[CCL26]
other gene names :
[CCL26; CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha; SCYA26; MIP-4-alpha; TSC-1]
uniprot entry name :
CCL26_HUMAN
host :
E Coli
sequence :
TRGSDISKTC CFQYSHKPLP WTWVRSSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
purity :
>=98% by SDS-PAGE gel and HPLC analyses.
form :
Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
storage stability :
Store at -20°C
other info1 :
Authenticity: Verified by N-terminal and Mass Spectometry analyses (when applicable). Endotoxin: Endotoxin level is <0.1 ng/ug of protein (<1EU/ug). Protein Content: Verified by UV Spectroscopy and or SDS-PAGE gel. Biological Activity: Determined by its ability to chemoattract human CCR3/HEK 293 cells using a concentration range of 1.0 -2.0 ug/mL.
other info2 :
Reconstitution: Centrifuge the vial prior to opening . Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortez. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C .
products categories :
Immunology; Proliferation and Cell Cycle; Chemotaxis
products description :
Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
ncbi gi num :
6685990
ncbi acc num :
Q9Y258.1
uniprot acc num :
Q9Y258
ncbi pathways :
Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL4-mediated Signaling Events Pathway (137933)
ncbi summary :
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]
uniprot summary :
CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family. Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: extracellular space. Molecular Function: chemokine activity. Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; immune response; chemotaxis; signal transduction; inflammatory response; positive regulation of cell migration
size1 :
0.005 mg
price1 :
125 USD
size2 :
0.02 mg
price2 :
195
size3 :
0.1 mg
price3 :
505
size4 :
0.5 mg
price4 :
1410
size5 :
1 mg
price5 :
2320
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!