product summary
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company name :
MyBioSource
product type :
protein
product name :
Human Neuritin
catalog :
MBS696013
quantity :
0.005 mg
price :
125 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS696013
products type :
Recombinant Protein
products full name :
Human Neuritin
products short name :
Neuritin
products name syn :
Recombinant Human Neuritin
other names :
Neuritin; Neuritin; neuritin; neuritin 1
other gene names :
NRN1; NRN1; NRN; dJ380B8.2; NRN
uniprot entry name :
NRN1_HUMAN
host :
E Coli
reactivity :
Species Reactivity: Human. Cross Reactivity: Rat
sequence :
AGKCDAVFK GFSDCLLKL GDSMANYPQ GLDDKTNIK TVCTYWEDF HSCTVTALT DCQEGAKDM WDKLRKESK NLNIQGSLF ELCGSGN
purity :
Above 98% as determined by SDS-PAGE Analysis.
storage stability :
At -20 degree C
other info1 :
Biological Activity: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml.
other info2 :
Cell Type: Neurons
products categories :
Neurosciences
products description :
Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.
ncbi gi num :
74752881
ncbi acc num :
Q9NPD7.1
uniprot acc num :
Q9NPD7
ncbi mol weight :
15,333 Da
ncbi summary :
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
uniprot summary :
NRN1: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Belongs to the neuritin family. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 6p25.1. Cellular Component: plasma membrane; synapse; cell junction. Biological Process: nervous system development
size1 :
0.005 mg
price1 :
125 USD
size2 :
0.02 mg
price2 :
195
size3 :
0.1 mg
price3 :
505
size4 :
0.5 mg
price4 :
1410
size5 :
1 mg
price5 :
2320
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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